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Metabolic Research
MOTS-c is a 16-amino-acid peptide described in research on mitochondrial signaling and metabolic regulation. Its name refers to a mitochondrial open reading frame within the 12S rRNA region. This DA listing provides 10 mg and 40 mg lyophilized research vial options.
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Volume pricing applies automatically from three vials and reaches 20% at twenty. Larger runs, institutional supply and custom timelines get a quote.
Ask about bulkVerified test results
Each batch is analyzed by an independent third-party laboratory before release. The lots below were tested by Chromate and ILS Laboratories. Below is the report for lot 4394A, summarized from the certificate the lab published.
Every lot we have published for this compound, grouped by the lab that tested it, newest first. Open any certificate below, exactly as the lab released it.
IdentityMOTS-c
Measured37.04mg
TestedMay 17, 2026
View certificate →On recordIdentityMOTS-c
Measured10.14mg
TestedMay 17, 2026
View certificate →On recordLabeled10mg
IdentityMOTS-c
Measured11.87mg
TestedFeb 8, 2026
View certificate →On recordTestedJan 30, 2026
View certificate →On recordTestedNov 3, 2025
View certificate →Side by side
Technical specifications
Peer-reviewed literature
Every reference below is a published, peer-reviewed record, linked to its PubMed entry. Provided for educational reference only - not product claims.
Important research notice
Not for human, veterinary, or food use. This product is sold exclusively for laboratory research purposes. It is not intended to diagnose, treat, cure, or prevent any disease, and has not been evaluated by the FDA.
All referenced publications and registries are sourced from peer-reviewed journals and official registries. They are provided for educational reference only and are not product claims.
By purchasing, you confirm you are a qualified researcher and will handle this product in accordance with all applicable laws and regulations.
Ready when you are
The lot on this page links to the signed certificate for that batch.
Lyophilized research material
MOTS-c is a 16-amino-acid peptide described in research on mitochondrial signaling and metabolic regulation. Its name refers to a mitochondrial open reading frame within the 12S rRNA region. This DA listing provides 10 mg and 40 mg lyophilized research vial options.
The 2015 discovery paper connected MOTS-c with the folate-purine pathway and AMPK-related cellular responses, and reported metabolic findings in mouse experiments. These results provide a foundation for laboratory investigation. They do not establish an administration protocol, human benefit, or equivalence between the study material and a commercial vial.
Lee et al., Cell Metabolism, 2015: the primary MOTS-c study. DOI: 10.1016/j.cmet.2015.02.009.
The listed quantity describes the labeled amount in each vial. Choose the option appropriate to your approved research plan and review its assigned lot. Do not apply the certificate from one vial quantity to another without confirming that the report identifies that material.
No. This is the standalone MOTS-c product. MitoPrime is a separately listed multi-component formulation containing NAD+, MOTS-c and 5-Amino-1MQ. Research on MOTS-c alone does not validate the finished mixture.
Use the COA portal to match the compound, selected option and shipping batch. Record the methods and results actually reported. HPLC purity and measured content describe different properties; neither should be inferred from the other.
Follow the label, batch documentation and validated laboratory procedures. Confirm stability for the specific formulation and experimental conditions. See the MOTS-c research guide or request documentation from DA.
Primary research relevant to the named compound or clearly identified component is linked below. Experimental results depend on identity, model and formulation.
Investigated movement of MOTS-c to the nucleus during metabolic stress and its relationship to adaptive gene regulation.
Described the mitochondrial-derived peptide and examined metabolic responses in experimental systems.
Retain the product label and lot number with the research record. Review the matching certificate of analysis for test coverage and reported results. Identity, analytical purity, measured content, sterility and endotoxin testing are distinct assessments; one does not establish the others.
Follow the supplied label and your laboratory’s validated handling and storage procedures. Record the vehicle, concentration and preparation date where relevant. Dry-material stability does not establish the shelf life of a prepared solution.
The listed milligrams refer to material per vial, not concentration or administration instructions. A prepared solution has its own concentration and stability requirements. Verify the exact selected option and shipping lot.
Open the linked certificate for the assigned lot or use the COA portal. Check sample identity, methods, date and reported measurements. A report for another lot or formulation is not a substitute.
The references describe the materials and conditions used by their authors. They do not establish that this commercial formulation was tested. For blends, evidence on an individual component does not validate the finished mixture or establish synergy.
The current certificate is matched to the selected product option and assigned shipping batch.
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