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MOTs-C research product
Lot4394AHPLC purity99.94%TestedJun 24, 2026ILS Laboratories · ISO/IEC 17025 accredited

Metabolic Research

MOTs-C

Lyophilized in the USA2174.6 g/molMitochondrial-derived 16-residue peptide

MOTS-c is a 16-amino-acid peptide described in research on mitochondrial signaling and metabolic regulation. Its name refers to a mitochondrial open reading frame within the 12S rRNA region. This DA listing provides 10 mg and 40 mg lyophilized research vial options.

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1
$44.99
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Your purchasing batch
4394A
Certificate on record · 7 lots published

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Verified test results

Every batch, independently verified.

Each batch is analyzed by an independent third-party laboratory before release. The lots below were tested by Chromate and ILS Laboratories. Below is the report for lot 4394A, summarized from the certificate the lab published.

ILS
ILS Laboratories
Independent · ISO/IEC 17025 accredited
PASS
Certificate of Analysis · COA-2026-954461
99.94%
Purity by HPLCSPEC ≥ 95.0%
Lot
4394A
Tested
Jun 24, 2026
Labeled
10mg
Measured
10.5mg
ISO 17025 accreditedFentanyl freeFull QC panel7 lots on record
MethodFull QC Panel
IssuedJul 30, 2026 · signed by the lab director
VerifyQR code and access code printed on the certificate
MOTs-C certificate of analysisOpen the 4394A certificate
View the signed certificate →
Full QC Panel✓ 7 passed · 1 reported
Appearance
Per certificate
Good
PASS
Identity
HPLC
Confirmed
PASS
Purity
HPLC
99.94%
SPEC ≥ 95.0%
PASS
Net peptide content
HPLC
10.5mg
REPORT ONLY
REPORTED
Sterility
PCR
No Growth
PASS
Endotoxins
LAL
<0.05EU/mL
SPEC ≤ 5 EU/mL
PASS
Heavy metals
ICP-MS
All Below Limits
USP <233>
PASS
Fentanyl screen
Per certificate
Not detected
PASS

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How Disguised compares.

Disguised
Typical supplier
Per-batch third-party COA
Yes
Rarely provided
ISO 17025 lab testing
Yes
Inconsistent
HPLC purity verified
Yes
Often unverified
Sterility tested
Yes
Rarely
Endotoxin tested
Yes
Rarely
Heavy metal tested
Yes
Rarely
Conformity testing
Yes
Not standard
Fentanyl screening
Yes
Not standard
Made & tested in the USA
Yes
Often overseas
Discreet, tracked shipping
Yes
Varies
Molecular Profile

What is MOTs-C?

Molecular FormulaC₁₀₁H₁₅₂N₂₈O₂₂S₂
Molecular Weight2174.6g/mol
Peptide ClassMitochondrial-derived 16-residue peptide
Storage Requirements

Stability information.

Avoid freeze/thaw cyclesProtect from lightRefrigerate after reconstitution
−20°C
Lyophilized powder, as shipped
The most stable form. Store cold and protected from light until it is reconstituted.
2–8°C
After reconstitution
Refrigerate once reconstituted and keep it protected from light.

Important research notice

Not for human, veterinary, or food use. This product is sold exclusively for laboratory research purposes. It is not intended to diagnose, treat, cure, or prevent any disease, and has not been evaluated by the FDA.

All referenced publications and registries are sourced from peer-reviewed journals and official registries. They are provided for educational reference only and are not product claims.

By purchasing, you confirm you are a qualified researcher and will handle this product in accordance with all applicable laws and regulations.

Ready when you are

Nothing ships without paperwork. Every lot is on record.

The lot on this page links to the signed certificate for that batch.

7Lots on record
99.94%HPLC purity, latest lot
17025ISO/IEC accredited lab
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View Full Product Description

Lyophilized research material

MOTs-C: product details and research reference

MOTS-c is a 16-amino-acid peptide described in research on mitochondrial signaling and metabolic regulation. Its name refers to a mitochondrial open reading frame within the 12S rRNA region. This DA listing provides 10 mg and 40 mg lyophilized research vial options.

What does the original MOTS-c research show?

The 2015 discovery paper connected MOTS-c with the folate-purine pathway and AMPK-related cellular responses, and reported metabolic findings in mouse experiments. These results provide a foundation for laboratory investigation. They do not establish an administration protocol, human benefit, or equivalence between the study material and a commercial vial.

Lee et al., Cell Metabolism, 2015: the primary MOTS-c study. DOI: 10.1016/j.cmet.2015.02.009.

10 mg versus 40 mg: what changes?

The listed quantity describes the labeled amount in each vial. Choose the option appropriate to your approved research plan and review its assigned lot. Do not apply the certificate from one vial quantity to another without confirming that the report identifies that material.

Is MOTS-c the same product as MitoPrime?

No. This is the standalone MOTS-c product. MitoPrime is a separately listed multi-component formulation containing NAD+, MOTS-c and 5-Amino-1MQ. Research on MOTS-c alone does not validate the finished mixture.

What should I check on the COA?

Use the COA portal to match the compound, selected option and shipping batch. Record the methods and results actually reported. HPLC purity and measured content describe different properties; neither should be inferred from the other.

Where can I find handling information?

Follow the label, batch documentation and validated laboratory procedures. Confirm stability for the specific formulation and experimental conditions. See the MOTS-c research guide or request documentation from DA.

Selected research and evidence

Primary research relevant to the named compound or clearly identified component is linked below. Experimental results depend on identity, model and formulation.

  1. MOTS-c and the nuclear stress responseCell-based mechanistic research · 2018 · PMID 29983246

    Investigated movement of MOTS-c to the nucleus during metabolic stress and its relationship to adaptive gene regulation.

  2. Discovery and metabolic characterization of MOTS-cCell and mouse research · 2015 · PMID 25738459

    Described the mitochondrial-derived peptide and examined metabolic responses in experimental systems.

Documentation and research handling

Retain the product label and lot number with the research record. Review the matching certificate of analysis for test coverage and reported results. Identity, analytical purity, measured content, sterility and endotoxin testing are distinct assessments; one does not establish the others.

Follow the supplied label and your laboratory’s validated handling and storage procedures. Record the vehicle, concentration and preparation date where relevant. Dry-material stability does not establish the shelf life of a prepared solution.

Product questions

What does the vial quantity describe?

The listed milligrams refer to material per vial, not concentration or administration instructions. A prepared solution has its own concentration and stability requirements. Verify the exact selected option and shipping lot.

Where is the batch-specific evidence?

Open the linked certificate for the assigned lot or use the COA portal. Check sample identity, methods, date and reported measurements. A report for another lot or formulation is not a substitute.

Do these studies test this finished product?

The references describe the materials and conditions used by their authors. They do not establish that this commercial formulation was tested. For blends, evidence on an individual component does not validate the finished mixture or establish synergy.

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