PE-22-28
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PE-22-28 – Neurotrophic Peptide for Neuronal Regeneration and Cognitive Research
Overview:
PE-22-28 is a synthetic neuroactive peptide derived from NAP (davunetide) analog structures, studied for its potential effects on neuronal growth, neuroprotection, and synaptic communication. This compound has become a focus of neurobiology and cognitive performance research due to its observed influence on neuronal differentiation, dendritic stability, and neurotrophic factor expression.
Scientific Background:
PE-22-28 is a short-chain peptide that interacts with microtubule-associated proteins and neurotrophic signaling cascades. In controlled studies, it has been shown to enhance neuronal survival and synaptic plasticity under oxidative or metabolic stress conditions. Research continues to explore its potential role in neurogenesis, cytoskeletal organization, and neuroinflammation modulation—making it a promising model for investigating cellular resilience and cognitive maintenance.
Why Researchers Study PE-22-28:
PE-22-28 serves as an innovative model for studying neuronal regeneration and cognitive health. Its unique mechanism of action across multiple neuroprotective pathways makes it valuable in exploring cell signaling, synaptic remodeling, and mitochondrial support under experimental conditions.
For Laboratory Research Use Only. Not for Human Consumption.
Only 2 left in stock
Description
Purity: ≥98% (HPLC)
Form: Lyophilized powder
Solubility: Sterile Water / Bacteriostatic Water
Molecular Weight (approx.): Sequence-verified; value reported per lot on COA
Appearance: White to off-white powder
Storage (dry): −20 °C long-term
After reconstitution: 2–8 °C (refrigerated); use within standard lab window
Handling: Minimize light exposure; avoid repeated freeze–thaw cycles
Reconstitution: Add sterile or bacteriostatic water under aseptic conditions; swirl gently to dissolve — do not vortex
Intended Research Applications
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Assay development for receptor binding and downstream second-messenger readouts
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Studies of peptide uptake, transport, and formulation stability in vitro
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Method development for peptide analytics (HPLC/UPLC method suitability, MS identity)
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Exploratory work on cell signaling dynamics and peptide structure–function relationships
Documentation
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COA: Available on request (includes identity confirmation by MS and HPLC chromatogram, lot-based)
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SDS: Provided with shipment
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Analytical: HPLC purity; identity confirmation by MS (lot-based)
? For laboratory research only. Not for human consumption, clinical use, or veterinary use. Handle in accordance with your institution’s safety and compliance protocols.