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Tesofensine research product
Lot060526HPLC purity99.97%TestedJun 19, 2026ILS Laboratories · ISO/IEC 17025 accredited

Neurocognitive Research

Tesofensine

328.3 g/mol

Tesofensine is a research compound sold here in capsules. Each capsule holds 500MCG. It is supplied for laboratory research only.

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Your purchasing batch
050526
Certificates for published lots are in the COA library

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Verified test results

Every batch, independently verified.

Each batch is analyzed by an independent third-party laboratory before release. The lots below were tested by Chromate and ILS Laboratories. Below is the report for lot 060526, summarized from the certificate the lab published.

ILS
ILS Laboratories
Independent · ISO/IEC 17025 accredited
PASS
Certificate of Analysis · COA-2026-EJFAQI
99.97%
Purity by HPLCSPEC ≥ 95.0%
Lot
060526
Tested
Jun 19, 2026
Labeled
500mcg
Measured
0.52mg
ISO 17025 accreditedFentanyl free2 lots on record
MethodPurity & Quant (HPLC), Heavy Metals (ICP-MS)
IssuedJun 21, 2026 · signed by the lab director
VerifyQR code and access code printed on the certificate
Tesofensine certificate of analysisOpen the 060526 certificate
View the signed certificate →
Certificate results✓ 5 passed · 1 reported
Appearance
Per certificate
Good
PASS
Identity
HPLC
Confirmed
PASS
Purity
HPLC
99.97%
SPEC ≥ 95.0%
PASS
Net content
HPLC
0.52mg
REPORT ONLY
REPORTED
Heavy metals
ICP-MS
All Below Limits
USP <233>
PASS
Fentanyl screen
Per certificate
Not detected
PASS

Every batch on record

Every lot we have published for this compound, grouped by the lab that tested it, newest first. Open any certificate below, exactly as the lab released it.

Open the COA portal →

Side by side

How Disguised compares.

Disguised
Typical supplier
Per-batch third-party COA
Yes
Rarely provided
ISO 17025 lab testing
Yes
Inconsistent
HPLC purity verified
Yes
Often unverified
Heavy metal tested
Yes
Rarely
Fentanyl screening
Yes
Not standard
Made & tested in the USA
Yes
Often overseas
Discreet, tracked shipping
Yes
Varies

Technical specifications

Compound Information

Read the Tesofensine research guide
Molecular Profile

What is Tesofensine?

Other namesNS2330, a serotonin, norepinephrine and dopamine reuptake inhibitor. Often searched as tesofensine peptide, but it is a small molecule, not a peptide
Molecular FormulaC₁₇H₂₃Cl₂NO
Molecular Weight328.3g/mol
Storage Requirements

Stability information.

Keep sealedProtect from lightAvoid humidity
Ships
What ships
Ships as a sealed container of capsules. Depending on the batch, that is a sealed plastic bottle, a sealed glass bottle or a professional-grade resealable pouch.
15–25°C
Sealed capsules, as shipped
Store at room temperature in the original sealed container, away from moisture and direct light.

Important research notice

Not for human, veterinary, or food use. This product is sold exclusively for laboratory research purposes. It is not intended to diagnose, treat, cure, or prevent any disease, and has not been evaluated by the FDA.

All referenced publications and registries are sourced from peer-reviewed journals and official registries. They are provided for educational reference only and are not product claims.

By purchasing, you confirm you are a qualified researcher and will handle this product in accordance with all applicable laws and regulations.

Ready when you are

Nothing ships without paperwork. Every lot is on record.

The lot on this page links to the signed certificate for that batch.

2Lots on record
99.97%HPLC purity, latest lot
17025ISO/IEC accredited lab
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Made in USAManufacturing originGMP CertifiedManufacturing standard

Encapsulated research material

Tesofensine: product details and research reference

Tesofensine is a research compound sold here in capsules. Each capsule holds 500MCG. It is supplied for laboratory research only.

Labs use it in models of monoamine transporter activity and dopamine signaling. Studies also cover norepinephrine pathways and serotonin-related biology. Other models examine appetite-related signaling and metabolic pathways.

Capsule details

Compoundtesofensine (development code NS2330)
Strength500MCG per capsule
Formatmicrogram capsules for research
Molecular formulaC17H23Cl2NO (free base)
Molecular weight328.3 g/mol (free base)

Is tesofensine a peptide?

No. Many people search for "tesofensine peptide," but it is not a peptide. It is a small molecule built on a tropane ring. It has no amino acids and no peptide bonds.

What tesofensine is

Tesofensine is a synthetic 3-phenyltropane. Its development code is NS2330, also written NS 2330 or NS-2330. It is a triple monoamine reuptake inhibitor. In lab work, it blocks the reuptake of dopamine, norepinephrine and serotonin.

A 2025 cryo-EM study mapped where it binds (Li et al., 2025). It sat in the central pocket of all three human transporters. It held each one in an outward-facing shape.

NeuroSearch and Boehringer Ingelheim first developed it for Parkinson's and Alzheimer's disease. Phase II trials did not show a consistent effect (Hauser et al., 2007), and that work stopped. It has not received full marketing authorization as a medicine.

Why tesofensine matters in research

It is studied for its link to monoamine transporter activity. These transporters matter in models of reward circuits and central nervous system control. They also appear in appetite-related signaling and energy-balance models.

Rodent studies have also looked at feeding circuits in the brain. One study in rats and transgenic mice examined GABAergic neurons in the lateral hypothalamus (Perez et al., 2024).

  • 500MCG capsule format
  • Studied in monoamine transporter pathway research
  • Relevant to dopamine, norepinephrine and serotonin models
  • Used in appetite-related and energy-balance pathway studies
  • Internal QA and in-house fulfillment

Identity, storage and shipping

Record the lot number in your notes. The certificate reports measured content per capsule, which can differ from the 500MCG label. Use the measured value for quantitative work. This page does not state a salt form, so compare identity data with the free base figures above.

Store the capsules at room temperature, 15 to 25°C, in the original sealed container. Keep them away from moisture and direct light. They ship in a sealed plastic bottle, a sealed glass bottle or a resealable pouch, depending on the batch.

Further reading

Tesofensine research guide · Tesofensine research guide

Documentation and research handling

Retain the product label and lot number with the research record. Review the matching certificate of analysis for test coverage and reported results. Identity, analytical purity, measured content, sterility and endotoxin testing are distinct assessments; one does not establish the others.

Follow the supplied label and your laboratory’s validated handling and storage procedures. Record the vehicle, concentration and preparation date where relevant. Dry-material stability does not establish the shelf life of a prepared solution.

Product questions

What does the labeled capsule or tablet amount mean?

It is the stated quantity per unit, separate from the number of units in the bottle. A purity percentage is not a measurement of milligrams per capsule or tablet. Use the matching lot report for the measurements actually performed.

Where is the batch-specific evidence?

Open the linked certificate for the assigned lot or use the COA portal. Check sample identity, methods, date and reported measurements. A report for another lot or formulation is not a substitute.

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